What does Gemistocytic mean?

A gemistocyte (/dʒɛˈmɪstəsaɪt/ jem-ISS-tə-syte; from Greek γέμιζω (gemizo) ‘to fill up’) is a swollen, reactive astrocyte.

What is Gemistocytic astrocytoma?

Gemistocytic astrocytomas were considered a specific type of diffuse astrocytic tumor, characterized by a prominent component of gemistocytes on histology, whereas now gemistocytic differentiation is merely a recognized pattern observed in astrocytic tumors.

What is pilocytic astrocytoma grade1?

Pilocytic astrocytomas, also known as juvenile pilocytic astrocytomas, are circumscribed astrocytic gliomas that tend to occur in young patients. They are considered WHO grade 1 tumors in the current WHO classification of CNS tumors and correspondingly have a relatively good prognosis.

What is pseudo Palisading?

Pseudopalisading, a visually similar finding, is the formation of hypercellular zones that typically surrounds necrotic tissue.

What is fibrillary astrocytoma?

Fibrillary astrocytoma is the most common histological subtype of diffuse or low-grade astrocytoma (WHO Grade II). These low-grade gliomas may occur anywhere within the CNS but are typically supratentorial, most commonly found in the frontal and temporal lobes.

Can a pilocytic astrocytoma become cancerous?

Pilocytic astrocytoma is a slowly growing neoplasia that represents the most frequent cerebral tumor in pediatric age. Malignant transformation is rare and it is usually related to previous radiotherapy.

Is pilocytic astrocytoma benign or malignant?

Pilocytic astrocytomas are low-grade gliomas, slow-growing tumors that arise from glial cells. Pilocytic astrocytoma is the most benign and most treatable of the gliomas.

What is Homer Wright rosette?

Homer Wright rosettes are differentiated tumor cells grouped around a central region containing neuropil (therefore its association with tumors of neuronal origin).

What is Antoni A?

Antoni A areas are composed of interlacing bundles of spindle cells (Schwann cells) with wavy or oval nuclei, eosinophilic cytoplasm, and indistinct cytoplasmic borders. Intranuclear vacuoles may be present. Antoni B areas are hypocellular and less compact than Antoni A areas.