What is the gold standard treatment for major depressive disorder?

Cognitive behavioral therapy (CBT) and interpersonal therapy are the psychotherapeutic approaches that have the best documented efficacy in the literature for management of depression.

Is duloxetine a good antidepressant?

Duloxetine demonstrated antidepressant efficacy at a dose of 60 mg qd in two placebo-controlled, randomized, double-blind studies and significantly improved remission rates compared with placebo.

What is the first-line treatment for major depression?

People with severe major depression usually need to be seen by a psychiatrist and sometimes need to be hospitalized. Choosing an antidepressant — For the initial treatment of severe depression, we use serotonin-norepinephrine reuptake inhibitors (SNRIs) or selective serotonin reuptake inhibitors (SSRIs).

Can you take Cymbalta and zoloft together?

Using sertraline together with DULoxetine can increase the risk of a rare but serious condition called the serotonin syndrome, which may include symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision.

Is Zoloft a good antidepressant?

Zoloft (sertraline) is a good and safe antidepressant that is also used to treat other psychiatric disorders such as panic disorder, post-traumatic stress disorder and obsessive compulsive disorder.

Can Seroquel alone treat depression?

May 6, 2008 (Washington) — The antipsychotic drug Seroquel may help battle major depression and generalized anxiety disorder, two new studies suggest. Seroquel is already approved to treat schizophrenia and bipolar disorder (formerly called manic-depressive illness).

What is the best antidepressant to start with?

The investigators recommend sertraline as the best choice for an initial antidepressant because it is available in generic form and is therefore lower in cost. They further recommend that sertraline, instead of fluoxetine or placebo, be the new standard against which other antidepressants are compared.