What is TRAb?

The thyrotropin receptor antibody (TRAb) test is a blood test that helps healthcare providers diagnose the autoimmune thyroid condition called Graves’ Disease. The antibodies it tests for are present in 90% of the people who have this disease. 1. Other names for the TRAb test include: Anti-Thyrotropin.

What is TRAb test of thyroid?

TSH receptor antibody (TRAb) is considered the gold standard diagnostic test for the autoimmunity of Graves’ disease (GD), which is commonly diagnosed clinically.

What does high TRAb mean?

A higher TRAb level at diagnosis was associated with higher thyroid hormone levels at diagnosis. This association was different in younger and older patients. In patients aged 55 years or older, a higher TRAb level was associated with higher thyroid hormone levels only if TRAb levels were below 10 U/L.

Is TRAb specific for Graves disease?

Because thyrotropin receptor autoantibodies (TRAb) are specific for Graves’ disease, we evaluated the ability of their levels and of their rate of change to predict long-term prognosis. In our study 216 consecutive patients with newly diagnosed Graves’ disease started a therapy with methimazole.

What is normal TRAb?

After the surgical procedure, TRAb levels were normal in all patients, the average values being 2.13 +/- 1.34 U/l. In 8 patients with recurrent hyperthyroidism (27%), TRAb concentration before the surgery was higher, mean -107.25 +/- 56.69 U/l.

What is TRAb negative?

TSH receptor antibodies (TRAbs) are the pathological hallmark of Graves’ disease, present in nearly all patients with the disease. Euthyroid Graves’ ophthalmopathy (EGO) is a well-recognized clinical entity, but its occurrence in patients with negative TRAbs is a potential source of diagnostic confusion.

Is TRAb the same as TSH?

TSH receptor autoantibodies (TRAb) are heterogeneous and may either mimic the action of TSH and cause hyperthyroidism as observed in Graves’ disease or alternatively, antagonize the action of TSH and cause hypothyroidism. The latter occurs most notably in the neonate as a result of a mother with antibodies due to AITD.

Do Graves antibodies go away?

Occasionally, the thyroid stimulating antibodies do go away in patients treated with antithyroid drugs, resulting in remission of the Graves’ disease and allowing for discontinuation of the medications. However, the thyroid stimulating antibodies may return causing the Graves disease to relapse.

What is negative TRAb?

Will I have Graves disease forever?

Graves’ disease is a lifelong condition. However, treatments can keep the thyroid gland in check. Medical care may even make the disease temporarily go away (remission): Beta-blockers: Beta-blockers, such as propranolol and metoprolol, are often the first line of treatment.