How does Alport syndrome affect eyes?
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How does Alport syndrome affect eyes?
It results in repeated episodes of eye itchiness, redness, light sensitivity, blurred vision and tears. This condition is annoying but again does not usually affect vision, although it is useful to remind your ophthalmologist if you have Alport syndrome so that they make the connection.
How do I know if I have Alport syndrome?
Blood in the urine (hematuria), the most common and earliest sign of Alport syndrome. Protein in the urine (proteinuria) High blood pressure (hypertension) Swelling in the legs, ankle, feet and around the eyes (called edema)
Does Alport syndrome cause blindness?
The characteristic ocular features of Alport syndrome are corneal opacities, anterior lenticonus and cataract, central perimacular and peripheral coalescing fleck retinopathies, and temporal retinal thinning. Rarely, posterior polymorphous corneal dystrophy, a macular hole, or a maculopathy impairs vision.
Are you born with Alport syndrome?
Alport syndrome is a rare genetic disorder characterized by progressive kidney disease and abnormalities of the inner ear and the eye. There are three genetic types. X-linked Alport syndrome (XLAS) is the most common; in these families affected males typically have more severe disease than affected females.
Anterior lenticonus is associated with Alport syndrome. This multisystem disorder has three major findings: chronic nephritis, nerve deafness, and specific ocular abnormalities. The common denominator is that basement membranes are affected in all three organs (12).
What do you need to know about Alport syndrome?
Summary Summary. Alport syndrome is a genetic condition characterized by kidney disease, hearing loss, and eye abnormalities. Most affected individuals experience progressive loss of kidney function, usually resulting in end-stage kidney disease.
How does Alport syndrome affect the inner ear?
Without treatment, affected individuals will experience end-stage renal disease. Alport syndrome also causes sensorineural hearing loss, or hearing loss that is due to the inner ear or the nerves not working properly.
What kind of disease is anterior lenticonus of cornea?
Alport Syndrome. Alport syndrome is a genetically heterogeneous condition characterized by nephropathy caused by thin glomerular basement disease with late-onset progressive sensorineural deafness and anterior lenticonus of the cornea of the eye (Haas, 2009).